I Made Cubane First
Chemiolis Chemiolis
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 Published On May 22, 2023

Check out ‪@ExtractionsAndIre‬ ! It's all in good fun and we talked about it before. Definitely watch his series for the spider infested shed synthesis of cubane.
Thanks to ‪@That_Chemist‬ for making the bromination mechanism and helping with some others
3D Molecule animation of Diels-Alder adduct made by ‪@reformlabs1050‬

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Cyclopentanone synthesis: http://www.orgsyn.org/demo.aspx?prep=...
Literature I used for all steps (except UV): https://doi.org/10.1016/j.bmcl.2013.1...
Literature I used for UV-step and onward: https://doi.org/10.1039/D3OB00231D
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0:00 - 0:52 Intro
0:52 - 5:23 Cyclopentanone
5:23 - 9:11 Cyclopentanone ethylene ketal
9:11 - 15:05 Tribromo
15:05 - 18:39 Diels-Alder adduct
18:39 - 23:11 Deprotection to diketone
23:11 - 25:27 Photoreaction to decahedron
25:27 - 29:53 Cubane dicarboxylic acid
29:53 - 33:32 Cubane dicarboxylate methyl ester
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