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Hello and welcome! My name is Anton and in this video, we will talk about the 2024 nobel prize in medicine and microrna
Links:
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993;75(5):843-854. doi:10.1016/0092-8674(93)90529-y
Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell. 1993;75(5):855-862. doi:10.1016/0092-8674(93)90530-4
Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kurodak MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinvasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000;408(6808):86-89. doi:10.1038/35040556
https://www.ncbi.nlm.nih.gov/pmc/arti...

Previous video about viruses:    • 8% of Human DNA Is Ancient Viruses An...  
0:00 2024 Nobel prize in medicine - microrna
0:55 How this started with worms
2:15 How this works in a nutshell in case you forgot
3:18 Discovery of a bizarre mutation: lin4 and lin14
5:05 Nobody cared though
5:30 Until everyone suddenly did
6:45 microRNA discoveries
9:00 Additional unexpected discoveries
#microrna #biology #nobelprize

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Credit:
The Nobel Committee for Physiology or Medicine. Ill. Mattias Karlén
Kelvinsong CC BY 3.0 https://en.wikipedia.org/wiki/MicroRN...
Bob Goldstein http://labs.bio.unc.edu/Goldstein/mov... CC BY-SA 3.0
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Bensaccount CC BY 3.0 https://en.wikipedia.org/wiki/Ribosom...

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