Edema (swelling of the legs, ankles, feet) is a very common condition. It is a sign that things are not right in the body, and many medications can cause this worrisome symptom. This video lists the 11 medications that cause leg swelling.

Sometimes you need to take a medicine. Keep in mind that there is almost always another medication choice if you have edema caused by your current one. If you are taking one of these 11 medicines that cause edema, talk with your doctor about changing to another.

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Medications discussed: Pramipexole,
Clonidine,
Trazadone,
MAO-Inhibitors - (Isocarboxazid (Marplan), Phenelzine (Nardil), Selegiline (Emsam), Tranylcypromine (Parnate), selegiline (Eldepryl, Zelapar, EMSAM) and rasagiline (Azilect)),
NSAID's - (ibuprofen, naproxen, diclofenac, and celecoxib, Ibuprofen, naproxen),
CCB's - (amlodipine (Norvasc), amlodipine + atorvastatin (Caduet), amlodipine + benazepril (Lotrel), amlodipine + valsartan (Exforge), amlodipine + telmisartan (Twynsta), amlodipine + olmesartan (Azor), amlodipine + olmesartan + hydroclorothiazide (Tribenzor), amlodipine + aliskiren + hydroclorothiazide, amlodipine + perindopril (Prestalia), clevidipine (Cleviprex), diltiazem (Cardizem), felodipine (Cardene, Cardene SR), isradipine, nicardipine, nimodipine, nisoldipine (Sular), verapamil (Calan))
beta-Blockers - acebutolol (Sectral), atenolol (Tenormin), betaxolol (Kerlone), bisoprolol fumarate (Zebeta), carvedilol (Coreg), esmolol (Brevibloc)
labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), nebivolol (Bystolic), penbutolol (Levatol), propranolol (Hemangeol, Inderal LA, Inderal XL, InnoPran XL), sotalol (Betapace, Sorine)
Corticosteroids - bethamethasone, (Celestone), prednisone (Prednisone), prednisolone (Orapred, Prelone), triamcinolone (Kenalog), methylprednisolone (Medrol, Depo-Medrol, Solu-Medrol), dexamethasone (Dexamethasone Intensol, DexPak 10 Day, DexPak)
gabapentin (Neurontin), pregabalin (Lyrica)
pioglitazone (Actos), rosiglitazone (Avandia)
Insulin (many brands)

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Ken D Berry, MD, is a Family Physician with 20 years of clinical practice.
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Any information on diseases and treatments available at this channel is intended for general guidance only and must never be considered a substitute for advice provided by a doctor or other qualified healthcare professional. Always seek the advice of your physician or other qualified health care professional with questions you may have regarding your medical condition. As an Amazon Associate, I earn from qualifying purchases.