Original paper: https://rupress.org/jem/article/221/7...

Video summary by Ian Cohn (University of Pennsylvania)

Cryptosporidium is an enteric pathogen that is a major cause of diarrheal disease worldwide. In this work, the authors engineer transgenic C. parvum to express MHCII-restricted model antigens and thereby dissect priming and effector functions in parasite-specific CD4+ T cells.

Keywords
Cryptosporidium, Immunology, Intestine, Infection, CD4 T cells, Dendritic cells